Thermo Fisher Scientific Core histone macro-H2A.2 Polyclonal Antibody
Core histone macro-H2A.2에 특이적인 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC에 적용 가능. Lyophilized 형태로 제공되며, 장기 보관 시 -20°C에서 안정적. 연구용으로만 사용.
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Thermo Fisher Scientific Core histone macro-H2A.2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300–1:2,000 |
| Immunohistochemistry (IHC) | 1:300–1:2,000 |
| Miscellaneous PubMed (Misc) | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from internal region of human Core histone macro-H2A.2 conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: Core histone macro-H2A.2.
Target Information
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription.
Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to cellular machineries that require DNA as a template.
Histones play a central role in transcription regulation, DNA repair, DNA replication, and chromosomal stability.
DNA accessibility is regulated via post-translational modifications of histones (histone code) and nucleosome remodeling.
May be involved in stable X chromosome inactivation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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