Thermo Fisher Scientific GPX1 Polyclonal Antibody
Human GPX1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 보존제가 포함되지 않아 필요 시 sodium azide 첨가를 권장합니다. Protein A 및 항원 친화 크로마토그래피로 정제되었으며, 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the C-terminus of the human GPX1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787961 |
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human GPX1.
Target Information
Glutathione peroxidases (Gpxs) are ubiquitously expressed proteins that catalyze the reduction of hydrogen peroxides and organic hydroperoxides by glutathione.
There are several isoforms differing in primary structure and localization:
- GPx1 (cGPx): Cytosolic/mitochondrial, selenium-dependent enzyme, first discovered GPx family member.
- GPx2 (GI-GPx): Expressed in gastrointestinal epithelium.
- GPx3 (pGPx): Extracellular plasma enzyme mainly expressed by the kidney.
- GPx4 (PH-GPx): Reduces hydroperoxides in membranes and lipoproteins.
- GPx5 (eGPx): Epididymis-specific secretory isoform.
All mammalian GPx family members, except for Cys-containing GPx3 and GPx5, possess selenocysteine at the active site.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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