Thermo Fisher Scientific Tyrosinase Polyclonal Antibody
Tyrosinase 단백질을 검출하기 위한 Rabbit Polyclonal Antibody. 인간 시료에 반응하며 WB, IHC, ICC, Flow Cytometry에 사용 가능. KLH 결합 합성 펩타이드로 면역생성. 2 mg/mL 농도의 액상 형태로 제공되며, 장기 보관 시 -20°C에서 보관 권장.
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Thermo Fisher Scientific Tyrosinase Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:50 |
| Immunocytochemistry (ICC/IF) | 1:10–1:50 |
| Flow Cytometry (Flow) | 1:10–1:50 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 486–513 amino acids from the C-terminal region of human Tyrosinase |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Size-exclusion, Dialysis, Ammonium sulfate precipitation |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2210852 |
Target Information
The enzyme encoded by this gene catalyzes the first two steps, and at least one subsequent step, in the conversion of tyrosine to melanin. It possesses both tyrosine hydroxylase and dopa oxidase catalytic activities and requires copper for function. Mutations in this gene can cause oculocutaneous albinism, while nonpathologic polymorphisms contribute to skin pigmentation variation. The human genome also contains a pseudogene similar to the 3′ half of this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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