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Thermo Fisher Scientific TIMP-4 Polyclonal Antibody
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Thermo Fisher Scientific TIMP-4 Polyclonal Antibody

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TIMP-4 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC, ELISA 등 다양한 응용에 적합. Human, Mouse, Rat 시료에 반응하며 Protein A로 정제됨. 1 mg/mL 농도의 액상 형태로 -20°C에서 보관.

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pk
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Thermo Fisher Scientific BS-0418R TIMP-4 Polyclonal Antibody 100 ul pk판매 단위 pk
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Thermo Fisher Scientific · Thermo Fisher Scientific TIMP-4 Polyclonal Antibody

Applications and Tested Dilutions

Application Tested Dilution
Western Blot (WB) 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC-P) 1:300
Immunohistochemistry (Frozen) (IHC-F) 1:100–1:500
Immunocytochemistry (ICC/IF) 1:50–1:200
ELISA 1:500–1:1,000

Product Specifications

Specification Detail
Species Reactivity Human, Mouse, Rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen KLH-conjugated synthetic peptide derived from human TIMP-4 (amino acids 161–224)
Conjugate Unconjugated
Form Liquid
Concentration 1 mg/mL
Purification Protein A
Storage Buffer 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains 0.02% ProClin 300
Storage Conditions -20°C
Shipping Conditions Ambient (domestic); Wet ice (international)

Target Information

Tissue inhibitor of metalloproteinase 4 (TIMP4) is encoded by the gene TIMP4 located on chromosome 3. It belongs to the family of TIMP genes and inhibits the activity of matrix metalloproteinases (MMPs), which degrade components of the extracellular matrix.
TIMP4 binds irreversibly to MMPs and inactivates them with zinc as a cofactor. The netrin domain of TIMP4 is involved in platelet recruitment and aggregation. Other biological functions include responses to cytokine and peptide hormone stimuli, as well as roles in the ovulation cycle and CNS development.


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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