Thermo Fisher Scientific COL4A6 Polyclonal Antibody
COL4A6 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot 및 IHC(Paraffin) 실험에 적합합니다. 인체, 마우스, 랫트 반응성 보유하며, 고순도 Affinity chromatography로 정제된 액상 형태입니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA599609
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human COL4A6 (Accession Q14031), corresponding to amino acid residues L1064–D1114 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818542 |
Product Specific Information
Antibody detects endogenous levels of total COL4A6.
Target Information
Type I collagen is the fibrillar collagen found in most connective tissues and is the only component of the collagen found in cartilage.
Mutations in this gene are associated with osteogenesis imperfecta, Ehlers-Danlos syndrome, and idiopathic osteoporosis.
Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor.
Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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