Thermo Fisher Scientific CD104 (Integrin Beta-4) (Squamous Cell Carcinoma Antigen) Monoclonal Antibody (UM-A9)
CD104 (Integrin Beta-4) 단일클론 항체로 인간 표피암 세포주에서 유래. ICC/IF, Flow Cytometry, Blocking Assay에 사용 가능. Protein A/G로 정제된 액상 형태로 4°C 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
| Blocking Assay (BLOCK) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UM-A9 |
| Immunogen | Human squamous cell carcinoma (UM-SCC1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Integrins are heterodimers comprised of alpha and beta subunits that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduce signals that regulate gene expression and cell growth.
This gene encodes the integrin beta 4 subunit, a receptor for laminins. It tends to associate with the alpha 6 subunit and plays a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: 3691-MSM1-P0_CD104_Integrin_beta_4_P16144-1_House_mouse.svg)
(이미지 파일명: 3691-MSM1-P0_CD104_Integrin_beta_4_P16144-1_House_mouse_PDP.jpeg)
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