
Thermo Fisher Scientific MSI2 Polyclonal Antibody
MSI2 단백질을 인식하는 Thermo Fisher Scientific의 Goat Polyclonal 항체로, Western blot 및 IHC(P) 실험에 적합합니다. 인간 및 마우스 시료에 반응하며, 비결합형 액상 형태로 제공됩니다. 줄기세포 관련 연구 및 MSI2 발현 분석에 유용합니다.
- 카탈로그번호
- PA5143187
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.3–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-SPDSLRDYFSK (aa 33–43) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933826 |
Product Specific Information
- This antibody is expected to recognize both reported isoforms (NP_620412.1; NP_733839.1).
- Tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
Msi2 (musashi homolog 2), also known as MSI2H, is a 328 amino acid RNA-binding protein localized in the cytoplasm and containing two RRM (RNA recognition motif) domains. It is expressed ubiquitously at low levels and plays a role in regulating mRNA translation, contributing to stem cell proliferation and maintenance in the central nervous system. Msi2 is phosphorylated posttranslationally and upregulated in response to brain injury, suggesting involvement in tissue regeneration. Chromosomal aberrations involving Msi2 are linked to chronic myeloid leukemia progression. Multiple isoforms exist due to alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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