Thermo Fisher Scientific alpha-2a Adrenergic Receptor Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 240-380 of human ADRA2A (NP_000672.3). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:alpha-2a Adrenergic Receptor,uniProtId:P08913-1,ncbiNodeId:9606,antigenRange:240-380,antigenLength:465,antigenImageFileName:PA5-120835_alpha-2a_Adrenergic_Receptor_P08913-1_Rabbit.svg,antigenImageFileNamePDP:PA5-120835_alpha-2a_Adrenergic_Receptor_P08913-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.59 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2914407

Product Specific Information

Positive test controls include: K-562, Mouse brain, Mouse Spinal cord. The target is usually found in the following locations: Cell membrane, Multi-pass membrane protein.

Immunogen sequence: RRTRVPPSRR GPDAVAAPPG GTERRPNGLG PERSAGPGGA EAEPLPTQLN GAPGEPAPAG PRDTDALDLE ESSSSDHAER PPGPRRPERG PRGKGKARAS QVKPGDSLPR RGPGATGIGT PAAGPGEERV GAAKASRWRG R

Target Information

Alpha-2-adrenergic receptors (ADRA2A) are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. ADRA2A mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G protein. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.