Thermo Fisher Scientific RANGAP1 Monoclonal Antibody (OTI1B4), TrueMAB
RANGAP1 단백질을 인식하는 고특이성 Mouse Monoclonal Antibody로 다양한 응용(WB, IHC, ICC, Flow)에 적합. HEK293T 세포에서 생산된 full-length human recombinant immunogen 사용. 고순도 Affinity chromatography 정제 및 안정적 PBS/BSA/glycerol buffer 제공.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Dog, Human, Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B4 |
| Immunogen | Full-length human recombinant protein of human RANGAP1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.81 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Ran is a small signaling GTPase involved in nucleocytoplasmic transport. It also plays roles in spindle aster formation and nuclear envelope reassembly during mitosis. Unlike Ras or Rho, Ran is not membrane-associated; instead, its accessory proteins RanGAP and RCC1 regulate the local concentration of RanGTP vs. RanGDP. Mammalian RanGAP binds to the nuclear pore through SUMOylation at its C terminus and subsequent interaction with nucleoporin Nup358.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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