Thermo Fisher Scientific LONP1 Polyclonal Antibody
LONP1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간 및 생쥐에 반응하며 Western blot에 적합. KLH 결합 합성 펩타이드 면역원 사용, Protein A 및 항원 친화 크로마토그래피로 정제. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between amino acids 389–418 from the central region of human LONP1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.35 |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2634671 |
Product Specific Information
Predicted to react with bovine, mouse, and rat based on sequence homology.
Target Information
This gene encodes a mitochondrial matrix protein belonging to the Lon family of ATP-dependent proteases. It mediates selective degradation of misfolded, unassembled, or oxidatively damaged polypeptides in the mitochondrial matrix. Additionally, it may act as a chaperone in the assembly of inner membrane protein complexes and regulate mitochondrial gene expression and genome integrity. Decreased expression has been observed in a patient with hereditary spastic paraplegia. Alternatively spliced transcript variants have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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