Thermo Fisher Scientific MFN2 Polyclonal Antibody
MFN2 단백질을 인식하는 Rabbit Polyclonal Antibody로 인간, 마우스, 랫트에 반응합니다. Western blot, IHC, ELISA에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 미토콘드리아 융합 및 신경계 질환 연구에 적합합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | View 4 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL | - |
| ELISA | Assay-Dependent | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | MFN2 antibody for a 17 amino acid peptide near the center of human MFN2 (amino acids 250–300). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2718665 |
Target Information
The MFN2 gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. It is involved in the regulation of vascular smooth muscle cell proliferation and may play a role in obesity pathophysiology. Mutations in MFN2 cause Charcot-Marie-Tooth disease type 2A2 and hereditary motor and sensory neuropathy VI, both peripheral nervous system disorders. Defects have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-72811_MFN2_O95140-1_Rabbit.svg, PA5-72811_MFN2_O95140-1_Rabbit_PDP.jpeg)
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