Thermo Fisher Scientific Phospho-Nrf2 (Ser40) Polyclonal Antibody
Human, Mouse, Rat 시료에서 인산화된 Nrf2(Ser40)를 검출하는 Rabbit Polyclonal Antibody. Western blot, IHC, ICC에 사용 가능. 항원 친화 크로마토그래피로 정제된 고품질 항체로, -20°C에서 안정적 보관 가능.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 | View 18 publications |
| Immunohistochemistry (IHC) | - | View 2 publications |
| Immunocytochemistry (ICC/IF) | 1:100 | View publications |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Bovine, Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human Nrf2 around the phosphorylation site of S40 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2691678 |
Product Specific Information
Predicted to react with Mouse and Rat samples.
Target Information
Nrf1 (also designated TCF11), Nrf2, and Nrf3 are bZIP transcription factors that heterodimerize with Maf proteins to bind MARE (Maf recognition elements) sequences.
Nrf2 is widely expressed and translocates to the nucleus after treatment with xenobiotics and antioxidants, which stimulate its release from the repressor protein Keap1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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