Thermo Fisher Scientific NDNL2 Polyclonal Antibody
Thermo Fisher Scientific NDNL2 Polyclonal Antibody는 인간, 마우스, 랫트 시료에서 NSMCE3 단백질을 검출하는 고품질 항체입니다. Western blot 및 IHC(Paraffin) 적용 가능하며, 고순도 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용됩니다.
- 카탈로그번호
- PA599776
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 1:1,000–1:3,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NSMCE3 (Accession Q96MG7), corresponding to amino acid residues F138–M188 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818709 |
Product Specific Information
Antibody detects endogenous levels of total MAGG1.
Target Information
The protein encoded by this gene is part of the SMC5-6 chromatin reorganizing complex and is a member of the MAGE superfamily. This intronless gene is a component of the SMC5-SMC6 complex, which is involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. It is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components, leading to disassembly in ALT-associated PML bodies (APBs).
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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