Thermo Fisher Scientific FAN Polyclonal Antibody
Human FAN 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC(P), ICC/IF 등 다양한 응용에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 0.10 mg/mL 농도의 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human FAN. Recombinant protein control fragment (Product #RP-93730). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.10 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2641497 |
Product Specific Information
Immunogen sequence:
EKVAMLTQIL EFGQTPKQLF VTPHPRRITP KFKSLSQTSS YNASMADSPG EESFEDLTEE SKTLAWNNIT KLQLHEHYKI HKEAVTGITV SRNGSSVFTT
Highest antigen sequence identity to the following orthologs:
- Mouse: 88%
- Rat: 91%
Target Information
This gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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