Thermo Fisher Scientific SP-C Polyclonal Antibody
Human, Mouse, Rat 반응성을 가진 Rabbit Polyclonal SP-C 항체로, IHC, ICC/IF, Flow Cytometry, ELISA 등 다양한 응용에 적합. Lung surfactant protein C 인식. Protein A 정제, 1 mg/mL 농도, -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human SP-C, amino acids 24–58 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes the pulmonary-associated surfactant protein C (SP-C), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins, including SPA, SPB, SPC, and SPD. The surfactant is secreted by alveolar cells and maintains pulmonary stability by reducing surface tension of fluids coating the lung. Mutations in this gene can cause pulmonary surfactant metabolism dysfunction type 2 (pulmonary alveolar proteinosis due to SP-C deficiency) and are associated with interstitial lung disease in infants, children, and adults. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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