Thermo Fisher Scientific SP-C Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Target Information

This gene encodes the pulmonary-associated surfactant protein C (SP-C), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins, including SPA, SPB, SPC, and SPD. The surfactant is secreted by alveolar cells and maintains pulmonary stability by reducing surface tension of fluids coating the lung. Mutations in this gene can cause pulmonary surfactant metabolism dysfunction type 2 (pulmonary alveolar proteinosis due to SP-C deficiency) and are associated with interstitial lung disease in infants, children, and adults. Alternatively spliced transcript variants encoding different isoforms have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.