Thermo Fisher Scientific Calmodulin Polyclonal Antibody
Calmodulin 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 분석에 적합합니다. 합성 펩타이드(119–136aa)를 면역원으로 사용하며, 동결건조 형태로 제공됩니다. 연구용으로만 사용되며, 고농도(500 µg/mL)로 안정적 보관이 가능합니다.
- 카탈로그번호
- PA578907
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Calmodulin Polyclonal Antibody
Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 0.5–1 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human Calmodulin |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2746023 |
Product Specific Information
The synthetic peptide sequence is 119–136aa (DEEVDEMIREADIDGDGQ).
Add 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
Calmodulin mediates the control of numerous enzymes, ion channels, aquaporins, and other proteins through Ca²⁺ binding. The calmodulin–Ca²⁺ complex stimulates various protein kinases and phosphatases. Together with CCP110 and centrin, it regulates the centrosome cycle and cytokinesis.
Calmodulin is a small, highly conserved calcium-binding protein (17 kDa) found in all eukaryotic cells, capable of binding up to four calcium ions. It acts as an intracellular receptor for regulatory calcium signals, undergoing conformational changes upon calcium binding that enhance its affinity for target proteins.
Calmodulin participates in energy metabolism, cell motility, exocytosis, cytoskeletal assembly, and intracellular modulation of cAMP and calcium levels. It contains 149 amino acids and four calcium-binding domains, playing key roles in growth, cell cycle, signal transduction, and neurotransmitter synthesis and release.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.