Thermo Fisher Scientific TMX2 Polyclonal Antibody

Applications

• Western Blot (WB): 0.2–1 µg/mL

Product Specifications

Product Specific Information

• Immunogen sequence:
  IRMGLLYITL CIVFLMTCKP PLYMGPEYIK YFNDKTIDEE LERDKRVTWI
• Storage recommendations:
  For short term use, store at 2–8°C up to 1 week.
  For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted homology:
  Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 85%

Target Information

This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain, and a C-terminal ER-retention sequence. This protein is enriched on the mitochondria-associated membrane of the ER via palmitoylation of two cytosolically exposed cysteines.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.