Thermo Fisher Scientific MAP2 Monoclonal Antibody (AP20)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500

View 1 publication 1 publication

Immunohistochemistry (IHC)

-

View 3 publications 3 publications

Immunohistochemistry (Paraffin) (IHC (P))

Assay-dependent

View 2 publications 2 publications

Immunocytochemistry (ICC/IF)

Assay-dependent

View 3 publications 3 publications

Product Specifications

Species Reactivity

Amphibian, Avian, Bovine, Human, Mouse, Rat, Xenopus

Published species

Guinea pig, Human, Mouse

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

AP20

Immunogen

Bovine protein.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

4.6 mg/mL

Storage buffer

Ascites

Contains

15mM sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_794874

Product Specific Information

Recommended positive controls: rat cerebral cortex.

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

MAP2 (Microtubule Associated Protein 2) exists in two high molecular weight forms (MAP2a & MAP2b) and a low molecular weight form. The expression of MAP2 is developmentally regulated and its multiple forms arise by alternative splicing of a single gene. MAP2 is involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dendrites, implicating a role in determining and stabilizing dendritic shape during neuron development. MAP2 is useful in studies of neuron structure in normal and malignant brain tissue as well as in degenerative diseases such as Alzheimer`s Disease (AD).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.