Thermo Fisher Scientific CRYGC Monoclonal Antibody (OTI1D6), TrueMAB
Human CRYGC 단백질을 인식하는 Mouse IgG2a 단클론 항체로 Western blot에 최적화됨. 고순도 친화 크로마토그래피 정제, 액상 형태로 공급. 렌즈 단백질 연구 및 백내장 관련 연구에 적합.
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- pk
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Applications
- Western Blot (WB)
Tested Dilution
- 1:4,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D6 |
| Immunogen | Full length human recombinant protein of human CRYGC produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Crystallins are separated into two classes: taxon-specific (enzyme) and ubiquitous. The ubiquitous class constitutes the major proteins of the vertebrate eye lens and maintains lens transparency and refractive index. Since lens fiber cells lose nuclei during development, crystallins are synthesized and retained throughout life, making them extremely stable proteins.
Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins form a superfamily. Gamma-crystallins are highly symmetrical, monomeric proteins lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are organized in a genomic cluster. Aging or mutations in these genes are implicated in cataract formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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