Thermo Fisher Scientific MAPK13 Monoclonal Antibody (OTI12C12), TrueMAB
MAPK13 단백질을 인식하는 Mouse 단일클론 항체로, Western blot과 Immunocytochemistry에 적합합니다. 고순도 Affinity chromatography로 정제되었으며, PBS/BSA/glycerol buffer에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:4,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI12C12 |
| Immunogen | Full length human recombinant protein of human MAPK13 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
MAPK13 (p38 delta) is a serine/threonine kinase that transduces a variety of extracellular signals, including cytokine and environmental stress responses. MAPK13 also regulates the differentiation of keratinocytes. This kinase is activated by various environmental stresses and proinflammatory cytokines. Activation requires phosphorylation by MAP kinase kinases or autophosphorylation triggered by interaction with MAP3K7IP1/TAB1. Substrates include transcription regulators ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, indicating its roles in stress-related transcription, cell cycle regulation, and genotoxic stress response. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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