Thermo Fisher Scientific NECAB3 Polyclonal Antibody
NECAB3 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. 인간 시료 반응성, WB 검증 완료. 액상 형태로 제공되며, 친화 크로마토그래피로 정제. 신경세포 단백질 연구 및 베타-아밀로이드 생성 조절 연구에 적합.
- 카탈로그번호
- PA544822
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB)
Tested Dilution: 0.2–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human NECAB3 (aa 1–50) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2605967 |
Product Specific Information
Peptide sequence:
MACAGLLTVC LLRPPAPQPQ PQTPRHPQLA PDPGPAGHTL FQDVFRRADKSequence homology:
Cow: 79%
Dog: 90%
Horse: 77%
Human: 100%
Mouse: 83%
Pig: 90%
Rat: 90%
Yeast: 100%
Target Information
The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2 and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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