Thermo Fisher Scientific COL6A3 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

This product can be used in direct ELISA.

Target Information

The COL6A3 gene encodes the alpha-3 chain, one of the three alpha chains of type VI collagen, a beaded filament collagen found in most connective tissues. The alpha-3 chain is larger than the alpha-1 and -2 chains due to additional subdomains similar to von Willebrand Factor type A domains. These domains interact with extracellular matrix proteins, playing a key role in matrix organization.
Mutations in type VI collagen genes are linked to Bethlem myopathy, a rare autosomal dominant proximal myopathy, and Ullrich congenital muscular dystrophy, a more severe autosomal recessive congenital myopathy. Multiple transcript variants exist, though not all have been fully described.
[Provided by RefSeq, Jun 2009]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.