Thermo Fisher Scientific COL6A3 Polyclonal Antibody
COL6A3 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot과 ELISA에 최적화되어 있습니다. 인간 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로 사용되며 보존제를 포함하지 않습니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:25,000–1:50,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human COL6A3/Collagen-VI protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography, Protein A |
| Storage buffer | PBS |
| Contains | No preservative |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2866899 |
Product Specific Information
This product can be used in direct ELISA.
Target Information
The COL6A3 gene encodes the alpha-3 chain, one of the three alpha chains of type VI collagen, a beaded filament collagen found in most connective tissues. The alpha-3 chain is larger than the alpha-1 and -2 chains due to additional subdomains similar to von Willebrand Factor type A domains. These domains interact with extracellular matrix proteins, playing a key role in matrix organization.
Mutations in type VI collagen genes are linked to Bethlem myopathy, a rare autosomal dominant proximal myopathy, and Ullrich congenital muscular dystrophy, a more severe autosomal recessive congenital myopathy. Multiple transcript variants exist, though not all have been fully described.
[Provided by RefSeq, Jun 2009]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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