Thermo Fisher Scientific MMP3 Polyclonal Antibody
MMP3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC, ELISA에 적용 가능. 인간, 생쥐, 랫트 반응성. 고순도 Affinity Chromatography 정제, 액상 형태, -20°C 보관. 연구용으로 세포외 기질 단백질 분석에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 385–477 of human MMP3 (NP_002413.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.914 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804809 |
Product Specific Information
Immunogen sequence:
VRKIDAAISD KEKNKTYFFV EDKYWRFDEK RNSMEPGFPK QIAEDFPGID SKIDAVFEEF GFFYFFTGSS QLEFDPNAKK VTHTLKSNSW LNC
Positive Samples: Mouse heart
Cellular Location: Extracellular matrix, extracellular space
Target Information
MMP3 (stromelysin-1) belongs to the peptidase M10A subfamily. It is secreted in its pro-protein form and activated by extracellular proteinase cleavage. MMP3 binds zinc and calcium ions and exhibits metallo-endopeptidase activity. The active enzyme degrades collagen, gelatin, fibronectin, and laminin, playing a role in wound repair and tissue remodeling. Mutations in the gene may lead to coronary heart disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지: PA5-88297_MMP3_P08254-1_Rabbit.svg, PA5-88297_MMP3_P08254-1_Rabbit_PDP.jpeg)
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