
Thermo Fisher Scientific PTF1A Monoclonal Antibody (OTI1H6), TrueMAB
PTF1A 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot에 최적화되어 있습니다. 인간, 마우스, 랫트에 반응하며, 동결건조 형태로 제공됩니다. 재조합 PTF1A 단백질로 면역화되었으며, 연구용으로만 사용 가능합니다.
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Applications
Tested Applications and Dilution
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1H6 |
| Immunogen | Full length human recombinant protein of human PTF1A produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
PTF1A is a component of the pancreas transcription factor 1 complex and plays an essential role in mammalian pancreatic development. It determines whether cells in the pancreatic buds proceed toward pancreatic organogenesis or revert to duodenal fates. PTF1A maintains exocrine pancreas-specific gene expression, including elastase 1 and amylase.
Mutations in this gene are associated with cerebellar agenesis, and loss of expression is observed in ductal-type pancreatic cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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