Thermo Fisher Scientific PCCA Monoclonal Antibody (OTI1B10), TrueMAB
PCCA 단백질을 인식하는 Mouse IgG1 단일클론 항체로 Western blot에 최적화되어 있습니다. Human, Mouse, Rat 반응성이 있으며, 동결건조 형태로 제공됩니다. 재구성 후 약 1 mg/mL 농도로 사용 가능하며, 연구용으로 적합합니다.
- 카탈로그번호
- CF810969
- 판매단위
- pk
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B10 |
| Immunogen | Full length human recombinant protein of human PCCA produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882) prior to use.
Target Information
PCCA is a key enzyme in the catabolic pathway of odd-chain fatty acids, isoleucine, threonine, methionine, and valine. It likely forms a dodecamer composed of six biotin-containing alpha subunits and six beta subunits, located in the mitochondrial matrix.
Defects in PCCA cause propionic acidemia type I (PA-1), a severe metabolic disorder characterized by episodic vomiting, lethargy, ketosis, neutropenia, thrombocytopenia, hypogammaglobulinemia, developmental retardation, and protein intolerance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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