Thermo Fisher Scientific TCAP Monoclonal Antibody (OTI3E7)
TCAP 단백질을 인식하는 마우스 단클론 항체로, Western blot과 IHC(Paraffin) 실험에 적합합니다. 고순도의 액상 항체로 PBS 버퍼에 보관되며, 인간 시료에 반응합니다. 근육 단백질 티틴 관련 연구에 유용합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3E7 |
| Immunogen | Full length human recombinant protein of TCAP produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2725485 |
Target Information
Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere and serves as a scaffold for myofibrils and other muscle-related proteins.
TCAP is a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and acts as a substrate of titin kinase, interactions thought to be critical to sarcomere assembly.
Mutations in the TCAP gene are associated with limb-girdle muscular dystrophy type 2G.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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