Thermo Fisher Scientific RBBP6 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1240-1355 of human RBBP6 (NP_008841.2). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RBBP6,uniProtId:Q7Z6E9-1,ncbiNodeId:9606,antigenRange:1240-1355,antigenLength:1792,antigenImageFileName:PA5-120294_RBBP6_Q7Z6E9-1_Rabbit.svg,antigenImageFileNamePDP:PA5-120294_RBBP6_Q7Z6E9-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.59 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2913866

Product Specific Information

Positive test controls include: K-562. The target is usually found in the following locations: Chromosome, Cytoplasm, Nucleus, centrosome, cytoskeleton, microtubule organizing center, nucleolus.

Immunogen sequence: SKVKQEKVKG KVRRKVTGTE GSSSTLVDYT STSSTGGSPV RKSEEKTDTK RTVIKTMEEY NNDNTAPAED VIIMIQVPQS KWDKDDFESE EEDVKSTQPI SSVGKPASVI KNVSTK

Target Information

This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.