Thermo Fisher Scientific RBBP6 Polyclonal Antibody
Thermo Fisher Scientific의 RBBP6 Polyclonal Antibody는 사람, 생쥐, 랫드 시료에 반응하는 토끼 유래 폴리클로날 항체입니다. Western blot과 ELISA에 적합하며, 고순도의 Affinity Chromatography 정제 방식으로 제조되었습니다. 세포 내 위치 연구 및 단백질 발현 분석에 활용됩니다.
- 카탈로그번호
- PA5120294
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1240–1355 of human RBBP6 (NP_008841.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.59 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2913866 |
Product Specific Information
- Positive test controls include: K-562
- Target localization: Chromosome, Cytoplasm, Nucleus, Centrosome, Cytoskeleton, Microtubule Organizing Center, Nucleolus
Immunogen sequence:
SKVKQEKVKG KVRRKVTGTE GSSSTLVDYT STSSTGGSPV RKSEEKTDTK RTVIKTMEEY NNDNTAPAED VIIMIQVPQS KWDKDDFESE EEDVKSTQPI SSVGKPASVI KNVSTK
Target Information
This gene encodes a cilia-associated protein belonging to the kinesin family. It plays a role in the Sonic Hedgehog (SHH) signaling pathway by regulating GLI transcription factors.
It functions as both a negative regulator (preventing inappropriate activation of GLI2) and a positive regulator (preventing processing of GLI3 into its repressor form).
Mutations in this gene are associated with various ciliopathies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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