Thermo Fisher Scientific Ku70 Polyclonal Antibody
Thermo Fisher Scientific의 Ku70 폴리클로날 항체로 인간 XRCC6 단백질을 인식합니다. Western blot, IHC, ICC/IF 등 다양한 응용에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS 버퍼에 40% 글리세롤 포함, 장기 보관 시 -20°C 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:2,500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human XRCC6. Recombinant protein control fragment (Product #RP-103007). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2791023 |
Product Specific Information
Immunogen sequence:
PPYFVALVPQ EEELDDQKIQ VTPPGFQLVF LPFADDKRKM PFTEKIMATP EQVGKMKAIV EKLRFTYRSD SFENPVLQQH FRNLEALALD LMEPEQAVDL
Target Information
XRCC6 (Ku70) is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa.
The complex functions as a single-stranded DNA-dependent, ATP-dependent helicase and may be involved in the repair of nonhomologous DNA ends such as those required for double-strand break repair, transposition, and V(D)J recombination.
High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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