Thermo Fisher Scientific GKN1 Polyclonal Antibody
Rabbit 유래 GKN1 폴리클로날 항체로, 인체 시료에 반응하며 IHC(P)에서 1:1,000–1:2,500 희석 비율로 사용 가능. 재조합 단백질 면역원 기반으로 높은 특이성과 재현성 제공. 냉장 또는 냉동 보관 가능하며 연구용으로 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:1,000–1:2,500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human GKN1. Recombinant protein control fragment (Product #RP-95688) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.10 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2791027 |
Product Specific Information
Immunogen sequence:
NDDNNNAGSG QQSVSVNNEH NVANVDNNNG WDSWNSIWDY GNGFAATRLF QKKTCIVHKM NKEVMPSIQ
Target Information
Gastrokine 1 (GKN1), also known as CA11, is a 185 amino acid secreted protein belonging to the gastrokine family with a BRICHOS domain and an asn-rich region.
GKN1 functions as an antioncogene and is reported to be down-regulated in human gastric cancer tissue compared to normal gastric mucosa.
It is predominantly expressed in the stomach and co-secreted with mucins, acting as a signaling growth factor with mitogenic activity that may help maintain gastric mucosal integrity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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