Thermo Fisher Scientific MAGEB1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:1,000-1:2,500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human MAGEB1. Recombinant protein control fragment (Product #RP-96775). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MAGEB1,uniProtId:P43366-1,ncbiNodeId:9606,antigenRange:25-155,antigenLength:347,antigenImageFileName:PA5-51744_MAGEB1_P43366-1_Rabbit.svg,antigenImageFileNamePDP:PA5-51744_MAGEB1_P43366-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2643677

Product Specific Information

Immunogen sequence: LKVAHATAAE KEECPSSSPV LGDTPTSSPA AGIPQKPQGA PPTTTAAAAV SCTESDEGAK CQGEENASFS QATTSTESSV KDPVAWEAGM LMHFILRKYK MREPIMKADM LKVVDEKYKD HFTEILNGAS R

Highest antigen sequence identity to the following orthologs: Mouse - 39%, Rat - 38%.

Target Information

This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is localized in the DSS (dosage-sensitive sex reversal) critical region, and expressed in testis and in a significant fraction of tumors of various histological types. This gene and other MAGEB members are clustered on chromosome Xp22-p21. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene, however, the full length nature of some variants has not been defined.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.