Thermo Fisher Scientific GAPDH Polyclonal Antibody
Rabbit polyclonal antibody against human GAPDH. Western blot validated. High specificity and sensitivity for GAPDH detection. Suitable as a loading control in protein expression studies. For research use only.
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- TAB1001
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Applications
Western Blot (WB)
- Tested dilution: 0.5 µg/mL
- View 23 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated peptide representing human GAPDH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | BBS, pH 8.4 |
| Contains | No preservative |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10709707 |
Product Specific Information
TAB1001 detects GAPDH in samples and has been successfully used in Western blot applications.
The immunogen is a KLH-conjugated peptide representing human GAPDH.
Target Information
GAPDH (Glyceraldehyde-3-phosphate dehydrogenase) is a catalytic enzyme involved in glycolysis. It exists as a tetramer of identical 37 kDa subunits and catalyzes the reversible reduction of 1,3-bisphosphoglycerate to glyceraldehyde 3-phosphate in the presence of NADPH.
Beyond glycolysis, GAPDH is ubiquitously expressed and participates in multiple cellular processes such as:
- DNA replication and repair
- Nuclear RNA export
- Membrane fusion and microtubule bundling
- Gene expression regulation during apoptosis
- Cellular mechanisms in neurodegenerative diseases (e.g., Alzheimer’s, Huntington’s)
GAPDH also associates with actin and tubulin and serves as a reliable loading control in Western blot analysis due to its stable expression across tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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