Thermo Fisher Scientific TCEB1 Polyclonal Antibody
Rabbit polyclonal antibody against human TCEB1 for ICC/IF applications. Recognizes recombinant human TCEB1 with 100% identity to mouse and rat orthologs. Purified by antigen affinity chromatography and supplied as liquid form for research use only.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human TCEB1. Recombinant protein control fragment (Product #RP-108139) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2663339 |
Product Specific Information
Immunogen sequence:
ETNEVNFREIP SHVLSKVCMY FTYKVRYTNS STEI
Highest antigen sequence identity to the following orthologs:
- Mouse: 100%
- Rat: 100%
Target Information
TCEB1, also known as protein elongin C, is a subunit of the transcription factor B (SIII) complex. The SIII complex, composed of elongins A/A2, B, and C, activates elongation by RNA polymerase II by suppressing transient pausing within transcription units.
Elongin A serves as the transcriptionally active component, while elongins B and C act as regulatory subunits. Elongin A2 is testis-specific and forms a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, inhibiting transcription elongation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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