Thermo Fisher Scientific Phospho-BAD (Ser112) Recombinant Rabbit Monoclonal Antibody (BADS112-B9)
Phospho-BAD (Ser112) 특이적 recombinant rabbit monoclonal antibody로, 높은 특이성과 재현성을 제공합니다. Human, Mouse, Rat에 반응하며 Flow Cytometry에 적합합니다. 안정적인 lot 간 일관성과 동물 유래 성분이 없는 제형입니다.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 1–1,000 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | BADS112-B9 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Ser112 of human phospho BAD |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2896993 |
Additional Formats
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages:
- High specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broad immunoreactivity due to rabbit immune repertoire
Target Information
The protein encoded by BAD is a member of the BCL-2 family, which regulates programmed cell death. BAD promotes apoptosis by forming heterodimers with BCL-xL and BCL-2, reversing their death repressor activity. Its proapoptotic activity is regulated through phosphorylation by kinases such as AKT and MAP kinase, and phosphatase calcineurin. Alternative splicing results in two transcript variants encoding the same isoform.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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