Thermo Fisher Scientific Mouse IL-4, Animal-Free Recombinant Protein, PeproTech
마우스 유래 IL-4 재조합 단백질로, 동물 유래 성분 없이 생산됨. 면역 조절 연구 및 세포 증식 활성 분석에 적합. ≥98% 고순도, 낮은 엔도톡신(<0.1 EU/µg). 건조 분말 형태로 -20°C 보관.
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Applications
ELISA (ELISA)
- Tested Dilution: -
- View 3 publications
Functional Assay
- Assay-dependent
- View reference
In vitro Assay (IV)
- Tested Dilution: -
- View 115 publications
Miscellaneous PubMed (Misc)
- Tested Dilution: -
- View 7 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Mouse |
| Published species | Fish, Human, Mouse |
| Expression System | E. coli |
| Amino Acid Sequence | MHIHGCDKNH LREIIGILNE VTGEGTPCTE MDVPNVLTAT KNTTESELVC RASKVLRIFY LKHGKTPCLK KNSSVLMELQ RLFRAFRCLD SSISCTMNES KSTSLKDFLE SLKSIMQMDY S |
| Molecular Weight | 13.5 kDa |
| Class | Recombinant |
| Type | Protein |
| Purity | ≥ 98% (SDS-PAGE & HPLC) |
| Endotoxin Concentration | < 0.1 EU/µg |
| Activity | ED50 ≤ 2.0 ng/ml (murine HT-2 cell proliferation assay), ≥ 5 × 10⁵ units/mg |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Purification | Purified |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient |
Product Specific Information
Recombinant Murine IL-4 is a 13.5 kDa globular protein containing 121 amino acid residues.
This product is shipped at ambient temperature. For storage, handling, and reconstitution information, please refer to the lot-specific Certificate of Analysis.
Target Information
Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, serving as a ligand for the interleukin 4 receptor.
IL-4 has a broad range of biological actions. The IL-4 receptor also binds IL-13, leading to overlapping functions between IL-4 and IL-13.
STAT6 acts as a key signal transducer in IL-4-mediated immune regulation.
The IL-4 gene, along with IL-3, IL-5, IL-13, and CSF2, forms a cytokine gene cluster on chromosome 5q, with IL-4 located near IL-13.
These genes are co-regulated by long-range elements spanning approximately 120 kilobases.
IL-4 delta 2 is a known splice variant of IL-4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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