Thermo Fisher Scientific CYP1B1 Polyclonal Antibody
Thermo Fisher Scientific의 CYP1B1 Polyclonal Antibody는 인간 CYP1B1 단백질을 인식하는 토끼 IgG 항체로, WB 및 IHC(P) 등 다양한 응용에 적합합니다. 단백질 G로 정제된 액상 형태이며, 4°C 단기 보관 및 -20°C 장기 보관이 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–10 µg/mL |
| In vitro Assay (IV) | Assay-Dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A portion of amino acids 400–450 of human CYP1B1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2540666 |
Target Information
CYP1B1 is a 543 amino acid intracellular protein localized to the endoplasmic reticulum. It belongs to the cytochrome P450 superfamily of enzymes, which are monooxygenases that catalyze reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids. This enzyme metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17β-estradiol, and is involved in metabolism of substances active in eye growth and differentiation, playing a putative role in ocular development. Mutations in CYP1B1 are known to cause primary congenital glaucoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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