Thermo Fisher Scientific ATG16L1 Polyclonal Antibody
ATG16L1 단백질을 인식하는 Rabbit Polyclonal 항체로, Human 및 Mouse 시료에 반응합니다. Western blot, IHC(P), ICC/IF 등 다양한 응용에 적합하며, Protein A 및 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:50 |
| Immunocytochemistry (ICC/IF) | 1:25 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide corresponding to amino acids 161–190 of human ATG16L1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long term, store at −20°C and avoid freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2552517 |
Target Information
Autophagy related protein 16L (ATG16L1) is encoded by the ATG16L gene located on chromosome 2 in humans. It is also known as WD30 or IBD10 (Inflammatory Bowel Disease 10). ATG12 and ATG5 conjugate and oligomerize with ATG16L1 to form the Atg16L complex (~800 kDa), which facilitates LC3 lipidation to phosphatidylethanolamine (PE). This ubiquitin-like conjugation system is a key marker for autophagy. The ATG16L complex, along with ATG18 and ATG21, prevents premature cleavage of ATG8-PE by Atg4 until autophagosome completion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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