Thermo Fisher Scientific Nectin 2 Monoclonal Antibody (502-57)
Mouse Nectin-2 단백질의 세포외 도메인을 인식하는 단클론 항체로, 인간 Nectin-2에도 교차 반응함. Western blot, IHC, Flow cytometry 등 다양한 응용 가능. Protein G로 정제된 액상 형태이며 4°C에서 보관.
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Thermo Fisher Scientific Nectin 2 Monoclonal Antibody (502-57)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:50 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:50 |
| Flow Cytometry (Flow) | 1:50 |
| Immunoprecipitation (IP) | 1:50 |
| Inhibition Assays (IA) | 1:50 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse |
| Host/Isotype | Rat / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 502-57 |
| Immunogen | Nectin 2 extracellular domain (Mouse, UniProt ID: P32507-1, range 1–530) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 100 µg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
| RRID | AB_3091088 |
Additional Formats
Product Specific Information
Monoclonal antibody 502-57 has been raised against the extracellular domain of mouse Nectin-2.
This antibody cross-reacts with human Nectin-2.
Target Information
The Nectin-2 gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and one Ig-like V-type domain.
It is a plasma membrane component of adherens junctions and serves as an entry receptor for certain mutant strains of herpes simplex virus and pseudorabies virus.
It plays a role in cell-to-cell viral spread and has been associated with variations in multiple sclerosis severity.
Alternate transcriptional splice variants encoding different isoforms have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일: MA5-49075_Nectin_2_P32507-1_Rat.svg, MA5-49075_Nectin_2_P32507-1_Rat_PDP.jpeg)
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