Thermo Fisher Scientific NOX1 Polyclonal Antibody
NOX1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. WB, IHC, ICC 등 다양한 응용에 적합. 고순도 Affinity chromatography 정제. 인간, 마우스, 랫트 반응성. 연구용으로만 사용.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 | View 3 publications |
| Immunohistochemistry (IHC) | – | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | – |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 | – |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NOX1 (Accession Q9Y5S8), corresponding to amino acid residues R471–H521 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852587 |
Product Specific Information
Antibody detects endogenous levels of total NOX1.
Target Information
Voltage-gated proton (hydrogen) channels play an important role in cellular defense against acidic stress.
NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox.
Three splice variants of NOX1 have been identified: NOH-1L, NOH-1S, and NOH-1Lv.
- NOH-1S: Voltage-gated proton channel regulating cellular pH, blocked by zinc.
- NOH-1L: Pyridine nucleotide-dependent oxidoreductase generating superoxide and possibly conducting H(+) ions.
NOX1 proteins may have therapeutic potential for ischemic diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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