Thermo Fisher Scientific Filamin B Polyclonal Antibody
Filamin B 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot 및 면역세포염색에 적합. 인간, 마우스, 랫트에 반응하며, 합성 펩타이드 항원을 기반으로 제작. 액상 형태, 1 mg/mL 농도, 친화 크로마토그래피로 정제됨.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human FLNB (Accession O75369), corresponding to amino acid residues I1695–K1745 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2899872 |
Product Specific Information
Antibody detects endogenous levels of total Filamin B.
Target Information
FOXK1 is expressed in these cells and regulates cell cycle progression through an interaction with its downstream target, the cyclin-dependent kinase inhibitor p21 (CIP).
Loss of FOXK1 in mice results in growth retardation and a severe impairment in skeletal muscle regeneration following injury.
FOXK1 also shows expression in immature tissues of brain, eye, heart, lung, and thymus, and is predominantly expressed in many malignant tissues such as tumors of the brain, colon, and lymph node.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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