Thermo Fisher Scientific LOXL1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 95-370 of human LOXL1 (NP_0055672) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:LOXL1,uniProtId:Q08397-1,ncbiNodeId:9606,antigenRange:95-370,antigenLength:574,antigenImageFileName:PA5-87701_LOXL1_Q08397-1_Rabbit.svg,antigenImageFileNamePDP:PA5-87701_LOXL1_Q08397-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.05 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804357

Product Specific Information

Immunogen sequence: RQAPSLPLPG RVGSDTVRGQ ARHPFGFGQV PDNWREVAVG DSTGMARART SVSQQRHGGS ASSVSASAFA STYRQQPSYP QQFPYPQAPF VSQYENYDPA SRTYDQGFVY YRPAGGGVGA GAAAVASAGV IYPYQPRARY EEYGGGEELP EYPPQGFYPA PERPYVPPPP PPPDGLDRRY SHSLYSEGTP GFEQAYPDPG PEAAQAHGGD PRLGWYPPYA NPPPEAYGPP RALEPPYLPV RSSDTPPPGG ERNGAQQGRL SVGSVYRPNQ NGRGLP; Positive Samples: HeLa, A375, A-549, BT-474, HT-1080, Mouse lung, Mouse heart, Rat heart; Cellular Location: extracellular space

Target Information

This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.