
Thermo Fisher Scientific Otelixizumab Humanized Recombinant Human Monoclonal Antibody
인간화된 재조합 단일클론 항체로 CD3E를 표적하며 T세포 신호전달 연구에 적합. ELISA 등 면역분석에 사용 가능. 단백질 A로 정제된 고순도 항체로 안정적인 액상 형태 제공. 자가면역 질환 관련 연구용으로 권장.
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Thermo Fisher Scientific Otelixizumab Humanized Recombinant Human Monoclonal Antibody
Applications
- ELISA (Assay-dependent)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Human / IgG1, lambda |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Immunogen | Human CD3E |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 3.95 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2910979 |
Product Specific Information
- Endotoxin level < 0.01 EU/µg by LAL method
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Store at 2–8°C for one week.
- Store at -20 to -80°C for twelve months from the date of receipt.
Target Information
Otelixizumab is a monoclonal antibody that binds to the CD3 receptor found on all T cells, which is involved in normal T cell signaling.
It is believed to inhibit the function of autoreactive T cells that propagate autoimmune diseases while inducing regulatory T cell pathways that promote immunological tolerance and suppress disease activity.
Tolerx is developing Otelixizumab for research related to type 1 diabetes, psoriasis, and other autoimmune diseases such as rheumatoid arthritis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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