Thermo Fisher Scientific CDKN2C Polyclonal Antibody
인간 CDKN2C 단백질에 특이적인 Rabbit Polyclonal 항체. Western blot과 IHC(P)에서 검증됨. 항원 친화 크로마토그래피로 정제된 액상 형태로 제공. 세포주기 조절 연구 및 CDK4/6 관련 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CDKN2C. Recombinant protein control fragment (Product # RP-92522) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2789816 |
Product Specific Information
Immunogen sequence:
LQTLLEFQAD VNIEDNEGNL PLHLAAKEGH LRVVEFLVKH TASNVGHRNH KGDTACDLAR LYGRNEVVSL MQANG
Target Information
The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein interacts with CDK4 or CDK6 and prevents activation of CDK kinases, functioning as a cell growth regulator controlling G1 phase progression. Ectopic expression suppresses growth of human cells with wild-type RB1 function. Knockout mouse studies suggest roles in spermatogenesis regulation and tumor suppression. Two alternatively spliced transcript variants encoding the same protein have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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