Thermo Fisher Scientific MAOB Polyclonal Antibody, MaxPab

Applications and Tested Dilution

• Western Blot (WB): 1:1,000

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
MSNKCDVVVV GGGISGMAAA KLLHDSGLNV VVLEARDRVG GRTYTLRNQK VKYVDLGGSY VGPTQNRILR LAKELGLETY KVNEVERLIH HVKGKSYPFR GPFPPVWNPI TYLDHNNFWR TMDDMGREIP SDAPWKAPLA EEWDNMTMKE LLDKLCWTES AKQLATLFVN LCVTAETHEV SALWFLWYVK QCGGTTRIIS TTNGGQERKF VGGSGQVSER IMDLLGDRVK LERPVIYIDQ TRENVLVETL NHEMYEAKYV ISAIPPTLGM KIHFNPPLPM MRNQMITRVP LGSVIKCIVY YKEPFWRKKD YCGTMIIDGE EAPVAYTLDD TKPEGNYAAI MGFILAHKAR KLARLTKEER LKKLCELYAK VLGSLEALEP VHYEEKNWCE EQYSGGCYTT YFPPGILTQY GRVLRQPVDR IYFAGTETAT HWSGYMEGAV EAGERAAREI LHAMGKIPED EIWQSEPESV DVPAQPITTT FLERHLPSVP GLLRLIGLTT IFSATALGFL AHKRGLLVRV

Target Information

MAOB (Monoamine Oxidase B), also known as MAO, BRAIN, or AMINE OXIDASE (FLAVIN-CONTAINING) B, is a protein encoded by the MAOB gene in humans.
It belongs to the flavin monoamine oxidase family and is located on Xp11.3.
MAOB catalyzes the oxidative deamination of biogenic and xenobiotic amines, playing a key role in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues.
This enzyme preferentially degrades benzylamine and phenylethylamine, and also degrades dopamine.
MAO-B inhibition increases dopamine activity and reduces hydrogen peroxide production, lowering reactive oxygen species.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.