Thermo Fisher Scientific FFA4 Polyclonal Antibody
Thermo Fisher Scientific의 FFA4 Polyclonal Antibody는 인간 FFA4 단백질을 인식하는 토끼 다클론 항체로, Western blot과 IHC(Paraffin)에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며 1 mg/mL 농도의 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide presents the carboxyl-terminal tail of human FFA4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | Dulbecco’s PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice (domestic); Dry ice (international) |
Target Information
An EST for GPR120 has been isolated from a human colon cancer library.
G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members predicted to exist.
All GPCRs share a structural motif consisting of seven membrane-spanning helices and exist in both active and inactive forms.
An array of activating ligands participate in the conformation of GPCRs, leading to signaling via G-proteins and downstream effectors.
Ongoing studies have also shown the vast series of reactions participating in the negative regulation of GPCRs.
This “turn-off” activity has tremendous implications for the physiological action of the cell and continues to drive pharmacological research for new drug candidates.
Two GPCR-targeted pharmaceuticals, Zyprexa (Eli Lilly) and Claritin (Schering-Plough), have achieved multi-billion dollar shares in the mental health and allergy markets, respectively.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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