Thermo Fisher Scientific Olig2 Polyclonal Antibody
Olig2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, Flow cytometry에 사용 가능. 인간, 마우스, 랫, 영장류 시료에 반응. 동결건조 형태로 제공되며, 4°C 또는 -20°C에서 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:250 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:250 | - |
| Flow Cytometry (Flow) | 1:250 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from human Olig2 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- The peptide is homologous in rat and mouse.
- Specificity: Olig2.
Target Information
This gene encodes a basic helix-loop-helix transcription factor expressed in oligodendroglial tumors of the brain. The protein regulates ventral neuroectodermal progenitor cell fate and is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia.
Located on chromosome 21, this region is implicated in learning deficits associated with Down syndrome.
Tissue specificity: Expressed in the brain, particularly in oligodendrocytes. Strongly expressed in oligodendrogliomas; weak to moderate in astrocytomas; variable in glioblastomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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