Thermo Fisher Scientific Versican Recombinant Rabbit Monoclonal Antibody (JB42-32)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunohistochemistry (Frozen) (IHC (F))

-

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Rhesus monkey

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

JB42-32

Immunogen

Recombinant protein within Human Versican aa 3,160-3,396 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Versican,uniProtId:P13611-1,ncbiNodeId:9606,antigenRange:3160-3396,antigenLength:3396,antigenImageFileName:MA5-34654_Versican_P13611-1_Rabbit.svg,antigenImageFileNamePDP:MA5-34654_Versican_P13611-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

TBS, pH 7.4, with 40% glycerol, 0.05% BSA

Contains

0.05% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles, store in dark

Shipping conditions

Wet ice

RRID

AB_2848562

Product Specific Information

Positive Control: Human spleen tissue, mouse brain tissue.

Target Information

Versican is a member of the family of large aggregating proteoglycans (also including aggrecan, brevican, and neurocan). The protein shows wide tissue distribution which includes fibrous, articular, and elastic cartilages, as well as nervous, epidermal, arterial, and loose connective tissues. Versican V1 has been shown to enhance cell proliferation, and also induce cell transformation and protect cells from apoptosis. This was demonstrated through its ability to downregulate the expression of proapoptotic Bad. Versican`s existence as a extracellular matrix protein in human airways has also lead to the discovery of an inflammatory role in asthmatics.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.