Thermo Fisher Scientific FOXC1 Polyclonal Antibody
FOXC1 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, IP 등 다양한 응용에 적합합니다. 액상 형태로 제공되며, 4°C 보관 및 Wet ice 배송 조건을 권장합니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific FOXC1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 375 and 425 of human Forkhead Box C1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Target Information
FOXC1 is a member of the forkhead family of transcription factors, characterized by a distinct DNA-binding forkhead domain.
Although its specific function is not fully understood, FOXC1 is involved in the regulation of the FGF19–FGFR4–MAPK pathway, contributing to the development and maintenance of anterior segment structures within the eye.
Mutations in the FOXC1 gene are associated with various ocular anomalies such as glaucoma, iridogoniodysgenesis, Peters anomaly, and Axenfeld-Rieger anomaly, which can involve structural and developmental defects of the cornea, iris, and facial bones.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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