
Thermo Fisher Scientific NOX1 Polyclonal Antibody
Rabbit 폴리클로날 항체로 인간 NOX1 단백질의 C-말단 유래 합성 펩타이드를 면역원으로 제작됨. Western blot에 적합하며 1:500–1:1,000 희석 사용 권장. 액상 형태, 1 mg/mL 농도. -20°C 보관, Wet ice 배송.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
- Publications: 참고 문헌 보기
Product Specifications
| 항목 | 내용 |
|---|---|
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide derived from the C-terminal region of human NOX1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2555873 |
Target Information
Voltage-gated proton (hydrogen) channels play an important role in cellular defense against acidic stress.
NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox.
Three splice variants of NOX1 have been identified: NOH-1L, NOH-1S, and NOH-1Lv.
- NOH-1S: Voltage-gated proton channel that regulates cellular pH and is blocked by zinc.
- NOH-1L: Pyridine nucleotide-dependent oxidoreductase that generates superoxide and may conduct H(+) ions as part of its electron transport mechanism.
- NOH-1S: Does not contain an electron transport chain.
NOX1 may have potential therapeutic applications in ischemic diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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