Thermo Fisher Scientific NOX1 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:1,000
• Publications: 참고 문헌 보기

Product Specifications

Target Information

Voltage-gated proton (hydrogen) channels play an important role in cellular defense against acidic stress.
NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox.
Three splice variants of NOX1 have been identified: NOH-1L, NOH-1S, and NOH-1Lv.

• NOH-1S: Voltage-gated proton channel that regulates cellular pH and is blocked by zinc.
• NOH-1L: Pyridine nucleotide-dependent oxidoreductase that generates superoxide and may conduct H(+) ions as part of its electron transport mechanism.
• NOH-1S: Does not contain an electron transport chain.

NOX1 may have potential therapeutic applications in ischemic diseases.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.