Thermo Fisher Scientific NOX3 Polyclonal Antibody
Thermo Fisher Scientific의 NOX3 Polyclonal Antibody는 인간 NOX3 내부 영역에서 유래한 합성 펩타이드로 제작된 토끼 IgG 항체입니다. Western blot 및 IHC(P) 분석에 적합하며, 내이 연구와 산화 스트레스 관련 메커니즘 연구에 활용됩니다. 액상 형태로 −20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 정보 없음
- View 1 publication
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:100
- View publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide derived from the internal region of human NOX3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2555871 |
Target Information
The NOX family of NADPH oxidases consists of seven transmembrane proteins that oxidize intracellular NADPH/NADH, facilitating electron transport across the membrane and reducing molecular oxygen to superoxide.
NOX3 is predominantly expressed in the inner ear and is involved in the biogenesis of otoconia/otolith. It is suggested that NOX3 is activated by the Transient Receptor Potential Vanilloid 1 (TRPV1), leading to increased reactive oxygen species levels in the inner ear, which in turn cause STAT1-mediated inflammation and hearing loss.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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