Thermo Fisher Scientific LILRB3 Monoclonal Antibody (326414)
LILRB3 단클론 항체(클론 326414)는 마우스 시료에 반응하며 Western blot, Flow cytometry 등 다양한 면역 분석에 사용됩니다. Rat IgG2a 아이소타입의 비결합 항체로, 단백질 A/G로 정제되었으며 동결건조 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1 µg/mL | View 2 publications |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunocytochemistry (ICC/IF) | - | View 2 publications |
| Flow Cytometry (Flow) | 2.5 µg per million cells | View publications |
| Immunoprecipitation (IP) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Mouse |
| Host / Isotype | Rat / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 326414 |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant mouse PIR-B Gly24–Gly635 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2608224 |
Product Specific Information
- In Western blots, this antibody does not cross-react with recombinant mouse PIR-A.
- Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, located in the chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors, containing two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs).
The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces inhibitory signals, regulating immune response activation. It is thought to control inflammatory responses and cytotoxicity, focusing the immune response and limiting autoreactivity. Multiple transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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